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Increased production and reduced urinary buffering of acid in uric acid stone formers is ameliorated by pioglitazone

Idiopathic uric acid nephrolithiasis is characterized by an overly acidic urine pH caused by the combination of increased acid production and inadequate buffering of urinary protons by ammonia. A large proportion of uric acid stone formers exhibit features of the metabolic syndrome. We previously de...

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Dades bibliogràfiques
Publicat a:Kidney Int
Autors principals: Maalouf, Naim M., Poindexter, John R., Huet-Adams, Beverley, Moe, Orson W., Sakhaee, Khashayar
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478507/
https://ncbi.nlm.nih.gov/pubmed/30795852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2018.11.024
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