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Increased production and reduced urinary buffering of acid in uric acid stone formers is ameliorated by pioglitazone

Idiopathic uric acid nephrolithiasis is characterized by an overly acidic urine pH caused by the combination of increased acid production and inadequate buffering of urinary protons by ammonia. A large proportion of uric acid stone formers exhibit features of the metabolic syndrome. We previously de...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Maalouf, Naim M., Poindexter, John R., Huet-Adams, Beverley, Moe, Orson W., Sakhaee, Khashayar
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478507/
https://ncbi.nlm.nih.gov/pubmed/30795852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.kint.2018.11.024
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