A collagen IV–derived peptide disrupts α(5)β(1) integrin and potentiates Ang2/Tie2 signaling

The angiopoietin (Ang)/Tie2 signaling pathway is essential for maintaining vascular homeostasis, and its dysregulation is associated with several diseases. Interactions between Tie2 and α(5)β(1) integrin have emerged as part of this control; however, the mechanism is incompletely understood. AXT107,...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:JCI Insight
Κύριοι συγγραφείς: Mirando, Adam C., Shen, Jikui, Silva, Raquel Lima e, Chu, Zenny, Sass, Nicholas C., Lorenc, Valeria E., Green, Jordan J., Campochiaro, Peter A., Popel, Aleksander S., Pandey, Niranjan B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2019
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478425/
https://ncbi.nlm.nih.gov/pubmed/30668550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.122043
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