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GC-MS metabolic profiling reveals Fructose-2,6-bisphosphate regulates branched chain amino acid metabolism in the heart during fasting

INTRODUCTION: As an insulin sensitive tissue, the heart decreases glucose usage during fasting. This response is mediated, in part, by decreasing phosphofructokinase-2 (PFK-2) activity and levels of its product fructose-2,6-bisphosphate. However, the importance of fructose-2,6-bisphosphate in the fa...

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Dettagli Bibliografici
Pubblicato in:Metabolomics
Autori principali: Batushansky, Albert, Matsuzaki, Satoshi, Newhardt, Maria F., West, Melinda S., Griffin, Timothy M., Humphries, Kenneth M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478396/
https://ncbi.nlm.nih.gov/pubmed/30830475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11306-019-1478-5
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