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Graft-to-Recipient Weight Ratio Associated With Tacrolimus Metabolism Following Pediatric Living Donor Liver Transplantations
OBJECTIVES: Tacrolimus (TAC) is an important immunosuppressant in liver transplantation. Since TAC is mainly metabolized by the liver enzymes CYP3A4 and 5, liver function is crucial for its pharmacokinetics (PK). Liver function is dynamic after liver transplantation; hence the PK of TAC metabolism a...
Gardado en:
| Publicado en: | J Pediatr Pharmacol Ther |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Pediatric Pharmacy Advocacy Group
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6478353/ https://ncbi.nlm.nih.gov/pubmed/31019407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-24.2.138 |
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