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Graft-to-Recipient Weight Ratio Associated With Tacrolimus Metabolism Following Pediatric Living Donor Liver Transplantations

OBJECTIVES: Tacrolimus (TAC) is an important immunosuppressant in liver transplantation. Since TAC is mainly metabolized by the liver enzymes CYP3A4 and 5, liver function is crucial for its pharmacokinetics (PK). Liver function is dynamic after liver transplantation; hence the PK of TAC metabolism a...

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Detalhes bibliográficos
Publicado no:J Pediatr Pharmacol Ther
Main Authors: Shoji, Kensuke, Miyairi, Isao, Inoue, Eisuke, Fukuda, Akinari, Sakamoto, Seisuke, Kasahara, Mureo
Formato: Artigo
Idioma:Inglês
Publicado em: Pediatric Pharmacy Advocacy Group 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478353/
https://ncbi.nlm.nih.gov/pubmed/31019407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5863/1551-6776-24.2.138
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