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Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth

The best measure to limit spread of contagious diseases caused by influenza A viruses (IAVs) is annual vaccination. The growing global demand for low-cost vaccines requires the establishment of high-yield production processes. One possible option to address this challenge is the engineering of novel...

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Bibliografische gegevens
Gepubliceerd in:PLoS Comput Biol
Hoofdauteurs: Laske, Tanja, Bachmann, Mandy, Dostert, Melanie, Karlas, Alexander, Wirth, Dagmar, Frensing, Timo, Meyer, Thomas F., Hauser, Hansjörg, Reichl, Udo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478349/
https://ncbi.nlm.nih.gov/pubmed/30973879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006944
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