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Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth

The best measure to limit spread of contagious diseases caused by influenza A viruses (IAVs) is annual vaccination. The growing global demand for low-cost vaccines requires the establishment of high-yield production processes. One possible option to address this challenge is the engineering of novel...

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Détails bibliographiques
Publié dans:PLoS Comput Biol
Auteurs principaux: Laske, Tanja, Bachmann, Mandy, Dostert, Melanie, Karlas, Alexander, Wirth, Dagmar, Frensing, Timo, Meyer, Thomas F., Hauser, Hansjörg, Reichl, Udo
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478349/
https://ncbi.nlm.nih.gov/pubmed/30973879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006944
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