Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth

The best measure to limit spread of contagious diseases caused by influenza A viruses (IAVs) is annual vaccination. The growing global demand for low-cost vaccines requires the establishment of high-yield production processes. One possible option to address this challenge is the engineering of novel...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Laske, Tanja, Bachmann, Mandy, Dostert, Melanie, Karlas, Alexander, Wirth, Dagmar, Frensing, Timo, Meyer, Thomas F., Hauser, Hansjörg, Reichl, Udo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2019
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478349/
https://ncbi.nlm.nih.gov/pubmed/30973879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006944
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