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Synthesis and Anticancer Activity Evaluation of Novel Phenanthridine Derivatives

Based on the structure of sanguinarine, fourteen phenanthridine derivatives were designed and synthesized in the current study. The cytotoxic activities of synthesized compounds were evaluated against five human cancer cell lines (MCF-7, PC3, Hela, A549, and HepG2 cell lines) via MTT assay. Among al...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Wan, Minghui, Zhang, Lei, Chen, Yiming, Li, Qiang, Fan, Wenli, Xue, Qingxia, Yan, Fang, Song, Weiguo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478010/
https://ncbi.nlm.nih.gov/pubmed/31058081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00274
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