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Synthesis and Anticancer Activity Evaluation of Novel Phenanthridine Derivatives

Based on the structure of sanguinarine, fourteen phenanthridine derivatives were designed and synthesized in the current study. The cytotoxic activities of synthesized compounds were evaluated against five human cancer cell lines (MCF-7, PC3, Hela, A549, and HepG2 cell lines) via MTT assay. Among al...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Wan, Minghui, Zhang, Lei, Chen, Yiming, Li, Qiang, Fan, Wenli, Xue, Qingxia, Yan, Fang, Song, Weiguo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6478010/
https://ncbi.nlm.nih.gov/pubmed/31058081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00274
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