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smCounter2: an accurate low-frequency variant caller for targeted sequencing data with unique molecular identifiers
MOTIVATION: Low-frequency DNA mutations are often confounded with technical artifacts from sample preparation and sequencing. With unique molecular identifiers (UMIs), most of the sequencing errors can be corrected. However, errors before UMI tagging, such as DNA polymerase errors during end repair...
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| Pubblicato in: | Bioinformatics |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477992/ https://ncbi.nlm.nih.gov/pubmed/30192920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty790 |
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