Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling

Enteroendocrine cells (EECs) produce hormones such as glucagon-like peptide 1 and peptide YY that regulate food absorption, insulin secretion, and appetite. Based on the success of glucagon-like peptide 1–based therapies for type 2 diabetes and obesity, EECs are themselves the focus of drug discover...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Roberts, Geoffrey P., Larraufie, Pierre, Richards, Paul, Kay, Richard G., Galvin, Sam G., Miedzybrodzka, Emily L., Leiter, Andrew, Li, H. Joyce, Glass, Leslie L., Ma, Marcella K.L., Lam, Brian, Yeo, Giles S.H., Scharfmann, Raphaël, Chiarugi, Davide, Hardwick, Richard H., Reimann, Frank, Gribble, Fiona M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2019
Assuntos:
Genetics/Genomes/Proteomics/Metabolomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477899/
https://ncbi.nlm.nih.gov/pubmed/30733330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0883
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