Comparison of Human and Murine Enteroendocrine Cells by Transcriptomic and Peptidomic Profiling

Enteroendocrine cells (EECs) produce hormones such as glucagon-like peptide 1 and peptide YY that regulate food absorption, insulin secretion, and appetite. Based on the success of glucagon-like peptide 1–based therapies for type 2 diabetes and obesity, EECs are themselves the focus of drug discover...

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Dades bibliogràfiques
Publicat a:Diabetes
Autors principals: Roberts, Geoffrey P., Larraufie, Pierre, Richards, Paul, Kay, Richard G., Galvin, Sam G., Miedzybrodzka, Emily L., Leiter, Andrew, Li, H. Joyce, Glass, Leslie L., Ma, Marcella K.L., Lam, Brian, Yeo, Giles S.H., Scharfmann, Raphaël, Chiarugi, Davide, Hardwick, Richard H., Reimann, Frank, Gribble, Fiona M.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2019
Matèries:
Genetics/Genomes/Proteomics/Metabolomics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477899/
https://ncbi.nlm.nih.gov/pubmed/30733330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db18-0883
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