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Mebendazole-induced M1 polarisation of THP-1 macrophages may involve DYRK1B inhibition
OBJECTIVE: We recently showed that the anti-helminthic compound mebendazole (MBZ) has immunomodulating activity by inducing a M2 to M1 phenotype switch in monocyte/macrophage models. In the present study we investigated the potential role of protein kinases in mediating this effect. RESULTS: MBZ pot...
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| Pubblicato in: | BMC Res Notes |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477744/ https://ncbi.nlm.nih.gov/pubmed/31010428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-019-4273-5 |
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