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Phage display of dynamic covalent binding motifs enables facile development of targeted antibiotics

Antibiotic resistance of bacterial pathogens poses an increasing threat to the wellbeing of our society and urgently calls for new strategies for infection diagnosis and antibiotic discovery. The antibiotic resistance problem to a large extent arises from extensive use of broad-spectrum antibiotics....

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: McCarthy, Kelly A., Kelly, Michael A., Li, Kaicheng, Cambray, Samantha, Hosseini, Azade S., van Opijnen, Tim, Gao, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477682/
https://ncbi.nlm.nih.gov/pubmed/29701966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b02461
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