High-throughput sequencing enhanced phage display enables the identification of patient-specific epitope motifs in serum

Phage display is a prominent screening technique with a multitude of applications including therapeutic antibody development and mapping of antigen epitopes. In this study, phages were selected based on their interaction with patient serum and exhaustively characterised by high-throughput sequencing...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Christiansen, Anders, Kringelum, Jens V., Hansen, Christian S., Bøgh, Katrine L., Sullivan, Eric, Patel, Jigar, Rigby, Neil M., Eiwegger, Thomas, Szépfalusi, Zsolt, Masi, Federico de, Nielsen, Morten, Lund, Ole, Dufva, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4650709/
https://ncbi.nlm.nih.gov/pubmed/26246327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12913
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