GENE-07. LIQUID BIOPSY DETECTION OF GENOMIC ALTERATIONS IN PEDIATRIC BRAIN TUMORS FROM CELL-FREE DNA IN PERIPHERAL BLOOD, CSF, AND URINE

Brain tumors require invasive neurosurgical procedures for diagnosis and tissue acquisition to guide precision medicine. Detection of tumor-derived cell-free DNA (ctDNA) would facilitate tumor profiling without risk of surgery-related morbidity. We aimed to validate a sample collection procedure and...

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Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: Pagès, Mélanie, Rotem, Denisse, Gydush, Gregory, Reed, Sarah, Rhoades, Justin, Ha, Gavin, Lo, Chris, Tracy, Adam, Jones, Robert, Becker, Sarah, Haller, Michaela, Chi, Susan, Kieran, Mark, Goumnerova, Liliana, Love, Christopher, Ligon, Keith, Wright, Karen, Adalsteinsson, Viktor, Beroukhim, Rameen, Bandopadhayay, Pratiti
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Genetics/Epigentics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477436/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.078
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