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THER-12. NOVEL IRON-TARGETED THERAPY IS HIGHLY EFFECTIVE IN TREATMENT-RESISTANT HIGH-GRADE GLIOMA IN VIVO

BACKGROUND: Chemo- and radioresistance are characteristic features of post-treatment high-grade glioma (HGG). The cell populations responsible for this treatment-resistant phenotype are glioma stem cells (GSCs). These GSCs have a high requirement for iron which is essential for tumor cell viability....

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: Al-Gizawiy, Mona, Wujek, Robert, Prah, Melissa, Knipstein, Jeffrey, Alhajala, Hisham, Doan, Ninh, Molino, Salvatore, Mirza, Shama, Chitambar, Christopher, Schmainda, Kathleen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Translational Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477424/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.219
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