HGG-14. IRRADIATION OF PEDIATRIC GLIOBLASTOMA CELLS INDUCES DOWNREGULATION OF TUMOR SUPPRESSOR MICRORNA GENES AND UPREGULATION OF VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)

INTRODUCTION: Recurrent glioblastoma (GBM) is known to be more aggressive and resistant to therapy when compared to the de-novo GBM tumor. Our previous in vivo studies showed that irradiated SJ-GBM2 cells exhibit greater radiological differences in angiogenesis and biological aggressiveness when com...

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Опубликовано в: :Neuro Oncol
Главные авторы: Alhajala, Hisham, Doan, Ninh, Al-Gizawiy, Mona, Knipstein, Jeffrey, Schmainda, Kathleen, Chitambar, Cristopher
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6012890/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy059.286
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