HGG-20. NOVEL IDENTIFICATION OF SIMULTANEOUS H3F3A K27M AND G34W MUTATIONS IN A PEDIATRIC DIFFUSE MIDLINE GLIOMA OF THE SPINAL CORD

We report a case of a diffuse midline glioma centered in the thoracic spinal cord in a 13-year old boy with co-occurring H3F3A hotspot missense mutations p.K27M and p.G34W. At 7-years of age, he presented with scoliosis and leg length discrepancy. MR imaging revealed an expansile, non-enhancing intr...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Cooney, Tabitha, Torkildson, Joseph, Sun, Peter, Perry, Arie, Solomon, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
High Grade Glioma
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477374/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.114
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