BIOL-04. DISTAL-LESS/DLX2 HOMEOBOX GENE REGULATION OF CHEMOKINE RECEPTOR CXCR4 - ROLE IN MIGRATION IN FOREBRAIN DEVELOPMENT AND CNS TUMORS

INTRODUCTION: Diffuse intrinsic pontine glioma (DIPG) have an extremely poor prognosis. Mutations of the genes encoding histone H3K27, especially H3K27M, are highly prevalent. There is reduced expression of the homeobox gene Dlx2 in DIPG with H3K27M mutations. Single cell RNA sequencing suggests tha...

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I publikationen:Neuro Oncol
Huvudupphovsmän: Japoni, Sara, Song, Xiaohua, Leng, Roger, Eisenstat, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Basic Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477350/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.017
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