LGG-16. PREDICTORS OF OUTCOME IN BRAF-V600E PEDIATRIC GLIOMAS TREATED WITH BRAF INHIBITORS: A REPORT FROM THE PLGG TASKFORCE

The BRAF-V600E mutation is found in 15–20% of pediatric low grade gliomas (PLGG) and result in worse outcome and higher risk of transformation to high grade gliomas (PHGG). Although ongoing trials are assessing the role of BRAF inhibitors (BRAFi) in these children, data are still limited. We aimed t...

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Publicat a:Neuro Oncol
Autors principals: Nobre, Liana, Zapotocky, Michal, Ryall, Scott, Stucklin, Ana Guerreiro, Bennett, Julie, Baroni, Lorena, Sumerauer, David, Zamecnik, Josef, Krskova, Lenka, Misove, Adela, Pavelka, Zdenek, Sterba, Jaroslav, Cruz, Ofelia, La Madrid, Andres Morales, Solano, Palma, Quiroga-Cantero, Eduardo, Canete, Adela, Guill, Julia Balaguer, Garre, Maria Luisa, Mascelli, Samatha, Iurilli, Valentina, Hauser, Peter, Frappaz, Didier, Conter, Cecile Faure, Hansford, Jordan, Amayiri, Nisreen, Morse, Helena, Sabel, Magnus, Bechensteen, Anne Grete, Su, Jack, Chintagumpala, Murali, Karajannis, Matthias, Kaur, Gurcharanjeet, Finlay, Jonathan, Osorio, Diana, Coven, Scott, Eisenstat, David, Wilson, Bev, Landeghem, Frank Van, Toledano, Helen, Dahiya, Sonika, Gauvain, Karen, Leary, Sarah, Nicolaides, Theodore, Finch, Elisabeth, Mueller, Sabine, Levy, Jean Mulcahy, Foreman, Nicholas, Ellison, David, Lassaletta, Alvaro, Larouche, Valerie, Mushtaq, Naureen, Milde, Till, Vantilburg, Cornelis, Witt, Olaf, Salgado, Duarte, Harting, Inga, Bornhorst, Miriam, Packer, Roger, Fernandes, Mariana, Injac, Sarah, Bavle, Abhi, Alderete, Daniel, Ramaswamy, Vijay, Taylor, Michael, Dirks, Peter, McKeown, Tara, Bartels, Ute, Bouffet, Eric, Hawkins, Cynthia, Tabori, Uri
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2019
Matèries:
Low Grade Glioma
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477313/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.159
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