IMMU-07. IMMUNOLOGIC TARGETING OF DIPG WITH H3K27M ENCODING RNA-NANOPARTICLES

BACKGROUND: Diffuse Intrinsic Pontine Glioma (DIPG) remains uniformly recalcitrant and thus necessitates development of novel targeted therapies. The histone mutation in H3K27M is conserved in the preponderance of DIPG patients and may be exploited as a neoepitope for cancer immunotherapy. We have d...

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Bibliografiska uppgifter
I publikationen:Neuro Oncol
Huvudupphovsmän: McGuiness, James, Mendez-Gomez, Hector, Stover, Brian, Weidert, Frances, Mitchell, Duane, Sayour, Elias
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2019
Ämnen:
Immunology/Immunotherapy
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477280/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.128
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