IMMU-07. IMMUNOLOGIC TARGETING OF DIPG WITH H3K27M ENCODING RNA-NANOPARTICLES

BACKGROUND: Diffuse Intrinsic Pontine Glioma (DIPG) remains uniformly recalcitrant and thus necessitates development of novel targeted therapies. The histone mutation in H3K27M is conserved in the preponderance of DIPG patients and may be exploited as a neoepitope for cancer immunotherapy. We have d...

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Udgivet i:Neuro Oncol
Main Authors: McGuiness, James, Mendez-Gomez, Hector, Stover, Brian, Weidert, Frances, Mitchell, Duane, Sayour, Elias
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019
Fag:
Immunology/Immunotherapy
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477280/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.128
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