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GENE-01. TUMOR MUTATIONAL BURDEN AND DRIVER MUTATIONS: FURTHER INSIGHT INTO THE GENOMIC LANDSCAPE OF PEDIATRIC BRAIN TUMORS
Tumor mutational burden (TMB) and driver mutations are potential biomarkers to predict efficacy of immune checkpoint inhibitors (ICPI). Studies demonstrated malignant gliomas with high TMB in children and adults may preferentially benefit from treatment with ICPI. Higher TMB has been found to relate...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6477265/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.072 |
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