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GENE-01. TUMOR MUTATION BURDEN AND DRIVER MUTATIONS: FURTHER INSIGHT INTO THE GENOMIC LANDSCAPE OF PEDIATRIC HIGH GRADE GLIOMAS
Pediatric high grade gliomas (HGG) have been described to have a higher tumor mutation burden (TMB) than low grade gliomas. A high TMB has been associated with improved objective immune checkpoint inhibitor (ICPI) response and progression-free survival in adult HGG. There is also data to suggest tha...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475036/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.072 |
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