SIG-02. RATIONAL TARGETING OF PRO-INVASIVE FGFR SIGNALING IN MEDULLOBLASTOMA

The metastatic potential of tumors depends in part on their response to growth factors available in the tumor microenvironment. We addressed how micro-environmental cues control tumor cell invasion in pediatric medulloblastoma (MB). We show that bFGF promotes MB tumor cell invasion through FGF recep...

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Detalles Bibliográficos
Publicado en:Neuro Oncol
Main Authors: Kumar, Karthiga Santhana, Brunner, Cyrill, Bruns, Dominique, Byrne, Ryan, Schneider, Gisbert, Schuster, Matthias, Zerbe, Oliver, Grotzer, Michael, Baumgartner, Martin
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Signalling
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6477202/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz036.206
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