The Systemic Administration of the Histamine H(1) Receptor Antagonist/Inverse Agonist Chlorpheniramine to Pregnant Rats Impairs the Development of Nigro-Striatal Dopaminergic Neurons

The dopaminergic and histaminergic systems are the first to appear during the development of the nervous system. Through the activation of H(1) receptors (H(1)Rs), histamine increases neurogenesis of the cortical deep layers, while reducing the dopaminergic phenotype (cells immunoreactive to tyrosin...

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Gepubliceerd in:Front Neurosci
Hoofdauteurs: Márquez-Valadez, Berenice, Aquino-Miranda, Guillermo, Quintero-Romero, Mijail-Oliver, Papacostas-Quintanilla, Helena, Bueno-Nava, Antonio, López-Rubalcava, Carolina, Díaz, Néstor Fabián, Arias-Montaño, José-Antonio, Molina-Hernández, Anayansi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2019
Onderwerpen:
Neuroscience
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476962/
https://ncbi.nlm.nih.gov/pubmed/31040765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00360
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