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The Systemic Administration of the Histamine H(1) Receptor Antagonist/Inverse Agonist Chlorpheniramine to Pregnant Rats Impairs the Development of Nigro-Striatal Dopaminergic Neurons

The dopaminergic and histaminergic systems are the first to appear during the development of the nervous system. Through the activation of H(1) receptors (H(1)Rs), histamine increases neurogenesis of the cortical deep layers, while reducing the dopaminergic phenotype (cells immunoreactive to tyrosin...

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Bibliographische Detailangaben
Veröffentlicht in:Front Neurosci
Hauptverfasser: Márquez-Valadez, Berenice, Aquino-Miranda, Guillermo, Quintero-Romero, Mijail-Oliver, Papacostas-Quintanilla, Helena, Bueno-Nava, Antonio, López-Rubalcava, Carolina, Díaz, Néstor Fabián, Arias-Montaño, José-Antonio, Molina-Hernández, Anayansi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476962/
https://ncbi.nlm.nih.gov/pubmed/31040765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00360
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