Reversal of apixaban induced alterations in haemostasis by different coagulation factor concentrates in patients after hip or knee replacement surgery

BACKGROUND: Apixaban is a direct oral anticoagulant (DOAC) with a specific inhibition of activated factor X (FXa). In case of bleeding or need of urgent surgery a direct antidote is not yet available. Off-label application of non-specific haemostatic agents, such as prothrombin complex concentrate (...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood Transfus
Egile Nagusiak: Schmidt, Katrin, Krüger, Kerstin, Langer, Elisabeth, Schmutzler, Martin, Johnen, Elke, Wernecke, Klaus D., von Heymann, Christian, Körber, Mareike K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Edizioni SIMTI - SIMTI Servizi Srl 2019
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476738/
https://ncbi.nlm.nih.gov/pubmed/29757137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2450/2018.0028-18
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