Haploinsufficiency of the brain-derived neurotrophic factor (BDNF) gene is associated with reduced pain sensitivity.

Rare pain insensitive individuals offer unique insights into how pain circuits function, and have led to the development of new strategies for pain control. We investigated pain sensitivity in humans with WAGR (Wilms tumor, aniridia, genitourinary anomaly, range of intellectual disabilities) syndrom...

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Gepubliceerd in:Pain
Hoofdauteurs: Sapio, Matthew R., Iadarola, Michael J., LaPaglia, Danielle M., Lehky, Tanya, Thurm, Audrey E., Danley, Kristen M., Fuhr, Shannon R., Lee, Mark D., Huey, Amanda E, Sharp, Stephen J., Tsao, Jack W., Yanovski, Jack A., Mannes, Andrew J., Han, Joan C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476691/
https://ncbi.nlm.nih.gov/pubmed/30855519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001485
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