Haploinsufficiency of the brain-derived neurotrophic factor (BDNF) gene is associated with reduced pain sensitivity.

Rare pain insensitive individuals offer unique insights into how pain circuits function, and have led to the development of new strategies for pain control. We investigated pain sensitivity in humans with WAGR (Wilms tumor, aniridia, genitourinary anomaly, range of intellectual disabilities) syndrom...

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Detalhes bibliográficos
Publicado no:Pain
Main Authors: Sapio, Matthew R., Iadarola, Michael J., LaPaglia, Danielle M., Lehky, Tanya, Thurm, Audrey E., Danley, Kristen M., Fuhr, Shannon R., Lee, Mark D., Huey, Amanda E, Sharp, Stephen J., Tsao, Jack W., Yanovski, Jack A., Mannes, Andrew J., Han, Joan C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476691/
https://ncbi.nlm.nih.gov/pubmed/30855519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001485
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