Haploinsufficiency of the brain-derived neurotrophic factor (BDNF) gene is associated with reduced pain sensitivity.

Rare pain insensitive individuals offer unique insights into how pain circuits function, and have led to the development of new strategies for pain control. We investigated pain sensitivity in humans with WAGR (Wilms tumor, aniridia, genitourinary anomaly, range of intellectual disabilities) syndrom...

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Publicat a:Pain
Autors principals: Sapio, Matthew R., Iadarola, Michael J., LaPaglia, Danielle M., Lehky, Tanya, Thurm, Audrey E., Danley, Kristen M., Fuhr, Shannon R., Lee, Mark D., Huey, Amanda E, Sharp, Stephen J., Tsao, Jack W., Yanovski, Jack A., Mannes, Andrew J., Han, Joan C.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476691/
https://ncbi.nlm.nih.gov/pubmed/30855519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/j.pain.0000000000001485
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