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Immune-Checkpoint Blockade Opposes CD8(+) T-cell Suppression in Human and Murine Cancer

Immune-checkpoint blockade enhances antitumor responses against cancers. One cancer type that is sensitive to checkpoint blockade is squamous cell carcinoma of the head and neck (SCCHN), which we use here to study limitations of this treatment modality. We observed that CD8(+) tumor infiltrating lym...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Res
Main Authors: Pfannenstiel, Lukas W., Diaz-Montero, C. Marcela, Tian, Ye F., Scharpf, Joseph, Ko, Jennifer S., Gastman, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476322/
https://ncbi.nlm.nih.gov/pubmed/30728151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-18-0054
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