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Tumor-derived exosomes induce CD8(+) T cell suppressors
BACKGROUND: The suppressive nature of immune cells in the tumor microenvironment plays a major role in regulating anti-tumor immune responses. Our previous work demonstrated that a soluble factor from tumor cells is able to induce a suppressor phenotype (SP) in human CD8(+) T cells typified by loss...
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| Udgivet i: | J Immunother Cancer |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5556362/ https://ncbi.nlm.nih.gov/pubmed/28806909 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-017-0269-7 |
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