Identification of a ligand-binding site on the Staphylococcus aureus DnaG primase C-terminal domain

The interface between the DnaG primase C-terminal domain (CTD) and the N-terminal domain of DnaB helicase is essential for bacterial DNA replication because it allows coordinated priming of DNA synthesis at the replication fork while the DNA is being unwound. Since these two proteins are conserved i...

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Bibliographic Details
Published in:Biochemistry
Main Authors: Catazaro, Jonathan, Periago, Jessica, Shortridge, Matthew D., Worley, Bradley, Kirchner, Andrew, Powers, Robert, Griep, Mark A.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476306/
https://ncbi.nlm.nih.gov/pubmed/28125218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01273
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