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Identification of a ligand-binding site on the Staphylococcus aureus DnaG primase C-terminal domain

The interface between the DnaG primase C-terminal domain (CTD) and the N-terminal domain of DnaB helicase is essential for bacterial DNA replication because it allows coordinated priming of DNA synthesis at the replication fork while the DNA is being unwound. Since these two proteins are conserved i...

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Publicat a:Biochemistry
Autors principals: Catazaro, Jonathan, Periago, Jessica, Shortridge, Matthew D., Worley, Bradley, Kirchner, Andrew, Powers, Robert, Griep, Mark A.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6476306/
https://ncbi.nlm.nih.gov/pubmed/28125218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b01273
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