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Ligands of Acid-Sensing Ion Channel 1a: Mechanisms of Action and Binding Sites

The proton-gated cationic channels belonging to the ASIC family are widely distributed in the central nervous system of vertebrates and play an important role in several physiological and pathological processes. ASIC1a are most sensitive to acidification of the external medium, which is the reason f...

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Veröffentlicht in:Acta Naturae
Hauptverfasser: Tikhonov, D. B., Magazanik, L. G., Nagaeva, E. I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: A.I. Gordeyev 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475867/
https://ncbi.nlm.nih.gov/pubmed/31024743
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