HACE1, an E3 Ubiquitin Protein Ligase, Mitigates Kaposi’s Sarcoma-Associated Herpesvirus Infection-Induced Oxidative Stress by Promoting Nrf2 Activity

Kaposi’s sarcoma-associated herpesvirus (KSHV)-induced activation of nuclear factor erythroid 2-related factor 2 (Nrf2) is essential for both the expression of viral genes (latency) and modulation of the host antioxidant machinery. Reactive oxygen species (ROS) are also regulated by the ubiquitously...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Kumar, Binod, Roy, Arunava, Asha, Kumari, Sharma-Walia, Neelam, Ansari, Mairaj Ahmed, Chandran, Bala
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475796/
https://ncbi.nlm.nih.gov/pubmed/30787155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01812-18
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