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Marek's Disease Virus Disables the ATR-Chk1 Pathway by Activating STAT3

Oncogenic virus replication often leads to genomic instability, causing DNA damage and inducing the DNA damage response (DDR) pathway. The DDR pathway is a cellular pathway that senses DNA damage and regulates the cell cycle to maintain genomic stability. Therefore, the DDR pathway is critical for t...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Lian, Xue, Bao, Chenyi, Li, Xueqi, Zhang, Xunhai, Chen, Hongjun, Jung, Yong-Sam, Qian, Yingjuan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475774/
https://ncbi.nlm.nih.gov/pubmed/30787154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02290-18
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