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The ATR Signaling Pathway Is Disabled during Infection with the Parvovirus Minute Virus of Mice

The ATR kinase has essential functions in maintenance of genome integrity in response to replication stress. ATR is recruited to RPA-coated single-stranded DNA at DNA damage sites via its interacting partner, ATRIP, which binds to the large subunit of RPA. ATR activation typically leads to activatio...

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Bibliographic Details
Main Authors: Adeyemi, Richard O., Pintel, David J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136315/
https://ncbi.nlm.nih.gov/pubmed/24965470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01412-14
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