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The ATR Signaling Pathway Is Disabled during Infection with the Parvovirus Minute Virus of Mice
The ATR kinase has essential functions in maintenance of genome integrity in response to replication stress. ATR is recruited to RPA-coated single-stranded DNA at DNA damage sites via its interacting partner, ATRIP, which binds to the large subunit of RPA. ATR activation typically leads to activatio...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4136315/ https://ncbi.nlm.nih.gov/pubmed/24965470 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01412-14 |
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