Significance of HER2 protein expression and HER2 gene amplification in colorectal adenocarcinomas

BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is an oncogenic driver, and a well-established therapeutic target in breast and gastric cancers. While the role of HER2 as a prognostic biomarker in colorectal adenocarcinomas (CRCs) remains uncertain, its relevance as a therapeutic target...

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Dettagli Bibliografici
Pubblicato in:World J Gastrointest Oncol
Autori principali: Wang, Xin-Yu, Zheng, Zhi-Xue, Sun, Yu, Bai, Yan-Hua, Shi, Yun-Fei, Zhou, Li-Xin, Yao, Yun-Feng, Wu, Ai-Wen, Cao, Deng-Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Baishideng Publishing Group Inc 2019
Soggetti:
Retrospective Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475672/
https://ncbi.nlm.nih.gov/pubmed/31040898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4251/wjgo.v11.i4.335
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