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ADAM10 controls the differentiation of the coronary arterial endothelium

The coronary vasculature is crucial for normal heart function, yet much remains to be learned about its development, especially the maturation of coronary arterial endothelium. Here, we show that endothelial inactivation of ADAM10, a key regulator of Notch signaling, leads to defects in coronary art...

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Publicat a:Angiogenesis
Autors principals: Farber, Gregory, Parks, Matthew M., Lustgarten Guahmich, Nicole, Zhang, Yi, Monette, Sébastien, Blanchard, Scott C., Di Lorenzo, Annarita, Blobel, Carl P.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475616/
https://ncbi.nlm.nih.gov/pubmed/30446855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10456-018-9653-2
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