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TNF-alpha Inhibits Pregnancy-Adapted Ca(2+) Signaling in Uterine Artery Endothelial Cells

Enhancement of vasodilation of uterine arteries during pregnancy occurs through increased connexin (Cx)43 gap junction (GJ) communication supporting more frequent and sustained Ca(2+) ‘bursts’. Such adaptation is lacking in subjects with preeclampsia (PE). Here we show TNF-alpha, commonly increased...

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Bibliografiske detaljer
Udgivet i:Mol Cell Endocrinol
Main Authors: Ampey, Amanda C, Boeldt, Derek S, Clemente, Luca, Grummer, Mary A, Yi, FuXian, Magness, Ronald R, Bird, Ian M
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475486/
https://ncbi.nlm.nih.gov/pubmed/30779937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2019.02.008
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