Adenoviral Transduction of EGFR into Pregnancy-Adapted Uterine Artery Endothelial Cells Remaps Growth Factor Induction of Endothelial Dysfunction

During pregnancy, uterine vascular vasodilation is enhanced through adapted Ca2+ signaling, facilitated through increased endothelial connexin 43 (Cx43) gap junctional communication (GJC). In preeclampsia (PE), this adaptive response is missing. Of note, the angiogenic factor VEGF can also act via S...

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Detalhes bibliográficos
Publicado no:Mol Cell Endocrinol
Main Authors: Clemente, Luca, Boeldt, Derek S., Grummer, Mary A., Morita, Mayu, Morgan, Terry K., Wiepz, Greg J., Bertics, Paul J., Bird, Ian M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6886699/
https://ncbi.nlm.nih.gov/pubmed/31550517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2019.110590
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