Phospholipid membranes drive abdominal aortic aneurysm development through stimulating coagulation factor activity

Abdominal aortic aneurysm (AAA) is an inflammatory vascular disease with high mortality and limited treatment options. How blood lipids regulate AAA development is unknown. Here lipidomics and genetic models demonstrate a central role for procoagulant enzymatically oxidized phospholipids (eoxPL) in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Allen-Redpath, Keith, Aldrovandi, Maceler, Lauder, Sarah N., Gketsopoulou, Anastasia, Tyrrell, Victoria J., Slatter, David A., Andrews, Robert, Watkins, W. John, Atkinson, Georgia, McNeill, Eileen, Gilfedder, Anna, Protty, Majd, Burston, James, Johnson, Sam R. C., Rodrigues, Patricia R. S., Jones, Dylan O., Lee, Regent, Handa, Ashok, Channon, Keith, Obaji, Samya, Alvarez-Jarreta, Jorge, Krönke, Gerhard, Ackermann, Jochen, Jenkins, P. Vince, Collins, Peter W., O’Donnell, Valerie B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2019
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6475397/
https://ncbi.nlm.nih.gov/pubmed/30944221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1814409116
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados