Proteasome Biology Is Compromised in White Matter After Asphyxic Cardiac Arrest in Neonatal Piglets

BACKGROUND: Neurological deficits in hypoxic‐ischemic encephalopathy, even with therapeutic hypothermia, are partially attributed to white matter injury. We theorized that proteasome insufficiency contributes to white matter injury. METHODS AND RESULTS: Neonatal piglets received hypoxia‐ischemia (HI...

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Detalles Bibliográficos
Publicado en:J Am Heart Assoc
Main Authors: Santos, Polan T., O'Brien, Caitlin E., Chen, May W., Hopkins, C. Danielle, Adams, Shawn, Kulikowicz, Ewa, Singh, Rashmi, Koehler, Raymond C., Martin, Lee J., Lee, Jennifer K.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474957/
https://ncbi.nlm.nih.gov/pubmed/30371275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009415
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