Combining Hypothermia and Oleuropein Subacutely Protects Subcortical White Matter in a Swine Model of Neonatal Hypoxic-Ischemic Encephalopathy

Neonatal hypoxia-ischemia (HI) causes white matter injury that is not fully prevented by therapeutic hypothermia. Adjuvant treatments are needed. We compared myelination in different piglet white matter regions. We then tested whether oleuropein (OLE) improves neuroprotection in 2- to 4-day-old pigl...

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Bibliografiske detaljer
Udgivet i:J Neuropathol Exp Neurol
Main Authors: Lee, Jennifer K, Santos, Polan T, Chen, May W, O’Brien, Caitlin E, Kulikowicz, Ewa, Adams, Shawn, Hardart, Henry, Koehler, Raymond C, Martin, Lee J
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2020
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819717/
https://ncbi.nlm.nih.gov/pubmed/33212486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnen/nlaa132
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