Quantifying in situ adaptive immune cell cognate interactions in humans

Two-photon excitation microscopy (TPEM) has revolutionized our understanding of adaptive immunity. However, TPEM usually requires animal models and is not amenable to the study of human disease. Recognition of antigen by T cells requires cell contact and is associated with changes in T cell shape. W...

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Bibliographic Details
Published in:Nat Immunol
Main Authors: Liarski, Vladimir M., Sibley, Adam, van Panhuys, Nicholas, Ai, Junting, Chang, Anthony, Kennedy, Domenick, Merolle, Maria, Germain, Ronald N., Giger, Maryellen L., Clark, Marcus R.
Format: Artigo
Language:Inglês
Published: 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474677/
https://ncbi.nlm.nih.gov/pubmed/30778242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41590-019-0315-3
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