Adjunctive dabigatran therapy improves outcome of experimental left-sided Staphylococcus aureus endocarditis

BACKGROUND: Staphylococcus aureus is the most frequent and fatal cause of left-sided infective endocarditis (IE). New treatment strategies are needed to improve the outcome. S. aureus coagulase promotes clot and fibrin formation. We hypothesized that dabigatran, could reduce valve vegetations and in...

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Publicat a:PLoS One
Autors principals: Lerche, Christian J., Christophersen, Lars J., Goetze, Jens Peter, Nielsen, Pia R., Thomsen, Kim, Enevold, Christian, Høiby, Niels, Jensen, Peter Ø., Bundgaard, Henning, Moser, Claus
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474597/
https://ncbi.nlm.nih.gov/pubmed/31002679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215333
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