Wolf-Hirschhorn Syndrome-Associated Genes Are Enriched in Motile Neural Crest Cells and Affect Craniofacial Development in Xenopus laevis

Wolf-Hirschhorn Syndrome (WHS) is a human developmental disorder arising from a hemizygous perturbation, typically a microdeletion, on the short arm of chromosome four. In addition to pronounced intellectual disability, seizures, and delayed growth, WHS presents with a characteristic facial dysmorph...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Mills, Alexandra, Bearce, Elizabeth, Cella, Rachael, Kim, Seung Woo, Selig, Megan, Lee, Sangmook, Lowery, Laura Anne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474402/
https://ncbi.nlm.nih.gov/pubmed/31031646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.00431
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