Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans

OBJECTIVE: Aging is associated with impaired insulin sensitivity and increased prevalence of type 2 diabetes. However, it remains unclear whether aging-associated insulin resistance is due to increased adiposity or other age-related factors. To address this question, we investigated the impact of ag...

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Veröffentlicht in:Obesity (Silver Spring)
Hauptverfasser: Ehrhardt, Nicole, Cui, Jinrui, Dagdeviren, Sezin, Saengnipanthkul, Suchaorn, Goodridge, Helen S., Kim, Jason K., Lantier, Louise, Guo, Xiuqing, Chen, Yii-Der I., Raffel, Leslie J., Buchanan, Thomas A., Hsueh, Willa A., Rotter, Jerome I., Goodarzi, Mark O., Péterfy, Miklós
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474357/
https://ncbi.nlm.nih.gov/pubmed/30801985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/oby.22418
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