High filamin-C expression predicts enhanced invasiveness and poor outcome in glioblastoma multiforme

BACKGROUND: Glioblastoma multiforme (GBM), the most common brain malignancy in adults, is generally aggressive and incurable, even with multiple treatment modalities and agents. Filamins (FLNs) are a group of actin-binding proteins that regulate the actin cytoskeleton in cells. However, the role of...

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Veröffentlicht in:Br J Cancer
Hauptverfasser: Kamil, Muhammad, Shinsato, Yoshinari, Higa, Nayuta, Hirano, Takuro, Idogawa, Masashi, Takajo, Tomoko, Minami, Kentaro, Shimokawa, Michiko, Yamamoto, Masatatsu, Kawahara, Kohichi, Yonezawa, Hajime, Hirano, Hirofumi, Furukawa, Tatsuhiko, Yoshimoto, Koji, Arita, Kazunori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6474268/
https://ncbi.nlm.nih.gov/pubmed/30867563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41416-019-0413-x
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